Myocardial injury in non-cardiac surgery: complexities and challenges

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The aetiology of myocardial injury after non-cardiac surgery

Recognition of myocardial injury after non-cardiac surgery is difficult, since strong analgesics (e.g. opioids) can mask anginal symptoms, and ECG abnormalities are subtle or transient. Thorough knowledge of the pathophysiological mechanisms is therefore essential. These mechanisms can be subdivided into four groups: type I myocardial infraction (MI), type II MI, non-ischaemic cardiac pathology...

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Association between intraoperative heart rate and postoperative myocardial injury in patients following non-cardiac surgery

Introduction Approximately 10% patients who undergo non-cardiac surgery show biochemical evidence of myocardial injury, which is associated with cardiac complications and death [1]. The aetiology and mechanisms of perioperative myocardial injury are incompletely understood. Observational studies have described associations between perioperative tachycardia and postoperative cardiac complication...

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[Myocardial protection in cardiac surgery.].

BACKGROUND AND OBJECTIVES Myocardial protection defines the set of strategies aiming at attenuating the intensity of myocardial ischemia-reperfusion injury during heart surgery and its harmful consequences on myocardial function. A better understanding of pathophysiological phenomena related to ischemia-reperfusion events and of the anesthetic-induced heart protection has given to the anesthesi...

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Myocardial injury after noncardiac surgery.

PURPOSE OF REVIEW Recent investigations have substantially improved our understanding of myocardial injury after noncardiac surgery (MINS). RECENT FINDINGS MINS is defined as a prognostically relevant myocardial injury due to ischemia that occurs during or within 30 days after noncardiac surgery. MINS occurs in 8% of adults undergoing major noncardiac surgery and is diagnosed with an elevated...

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ژورنال

عنوان ژورنال: Singapore Medical Journal

سال: 2020

ISSN: 0037-5675

DOI: 10.11622/smedj.2020004